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HPV Test

👤by AP 0 comments 🕔Tuesday, March 4th, 2014

Of the more than 100 types of papillomaviruses (HPVs) that infect humans, more than 40 types can infect the anogenital tract (genital tract and anus) of men and women and cause genital warts (known as condylomata acuminata or venereal warts). A subgroup of the HPVs that infect the anogenital tract (genital tract and anus) can lead to precancerous changes in the uterine cervix and cause cervical cancer or other genital cancers in women. The HPV types that cause cervical cancer also have been linked with both anal and penile cancer in men.

The most common HPV types that infect the anogenital tract are HPV types 6, 11, 16, and 18 (HPV-6, HPV-11, HPV-16, and HPV-18), although other HPV types can also infect the anogenital tract. Among these, HPV-6 and HPV-11 are most commonly associated with benign lesions such as genital warts and mild dysplasia of the cervix (potentially precancerous changes in the appearance of cervical cells under a microscope) and are termed "low-risk" HPV types. In contrast, HPV-16 and HPV-18 are the types found in the majority of cervical and anogenital cancers as well as severe dysplasia of the cervix. These belong to the so-called "high-risk" group of HPVs. Twelve other HPV types have also been identified as causes of cervical and other genital cancers, although these are less common that HPV-16 and -18.

HPV infections are transmitted primarily by sexual intimacy, and the risk of infection increases as the number of sexual partners increase.

Who Should Get the HPV Vaccine?

Human papillomavirus (HPV) infection of the cervix can lead to cervical cancer. A vaccine designed to prevent cervical cancer and other diseases caused by infection with HPVs was approved for use in the U.S. in June 2006. This was the first vaccine to be developed against a known risk factor for the development of a cancer.

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