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Barbiturates

👤by AP 0 comments 🕔Tuesday, September 30th, 2014

Barbiturates are central nervous depressants. They reduce the activity of nerves causing muscle relaxation. They can reduce heart rate, breathing, and blood pressure. All barbiturates affect gamma-aminobutyric acid (GABA), a neurotransmitter (chemical) that nerves use to communicate with one another.

For what conditions are barbiturates prescribed?

Barbiturates are medications used for treating headaches, insomnia, and seizures. Barbiturates are one of the older classes of medications.

What are examples barbiturates of available in the US?

Examples of barbiturates available in the US include:

amobarbital (Amytal) butabarbital (Butisol) pentobarbital (Nembutal) secobarbital (Seconal) belladonna and phenobarbital (Donnatal) butalbital/acetaminophen/caffeine (Esgic, Fioricet) butalbital/aspirin/caffeine (Fiorinal Ascomp, Fortabs) What are the side effects of barbiturates?

Common side effects of barbiturates are:

dizziness, lightheadedness, sedation, headache, nausea, and abdominal pain.

Barbiturates can slow breathing, reduce heart rate, and they can be habit forming.

What drugs interact with barbiturates?

Barbiturates should be used with caution with some medications because they accelerate the breakdown of these medications leading to decreased effectiveness. Examples of these medications that interact with barbiturates include:

atazanavir (Reyataz), boceprevir (Victrelis), lurasidone (Latuda), ranolazine (Ranexa), telaprevir (Incivek), voriconazole, (Vfend), and ritonavir (Norvir).

Concomitant use of barbiturates and other central nervous system depressant medications should be used with caution because concomitant use can lead to excessive sedation, lethargy, and in severe cases coma and death. Examples of these medications that should be used with caution with other central nervous system depressant medications such as:

alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), zolpidem (Ambien), and zaleplon (Sonata).

Medically Reviewed by a Doctor on 9/30/2014

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Article Credits / Source

AP / MedicineNet.com

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