Daily Health Headlines

HIV Can Damage Brain Early On, Study Says

👤by Robert Preidt 0 comments 🕔Friday, April 3rd, 2015

THURSDAY, April 2, 2015 (HealthDay News) -- HIV can spread to and develop in people's brains in the early stages of infection, new research shows.

The findings highlight the need for screening and early treatment of infection with HIV, the virus that causes AIDS, the researchers said.

"Any delay runs the risk that the virus could find refuge and cause damage in the brain, where some medications are less effective, potentially enabling it to re-emerge, even after it is suppressed in the periphery," said Dianne Rausch, director of the division of AIDS research at the U.S. National Institute of Mental Health (NIMH).

The researchers compared evidence of HIV activity in samples of blood and spinal fluid from 72 untreated HIV-infected patients.

The investigators found that 10 percent to 22 percent of the patients showed evidence of HIV replication or inflammation -- which suggests an active infectious process -- in the brain at different times within the first two years of infection. These signs persisted over time in about 16 percent of the patients, they said.

In some patients, HIV began replicating in the brain within the first four months of infection, according to the study published recently in the journal PLoS Pathogens.

The researchers also found that HIV in the central nervous system can evolve into genetically different forms than HIV in other parts of the body.

If the mutated forms of HIV in the brain are treatment-resistant, they could re-infect the rest of the body after seemingly successful treatment for HIV, Rausch said in a news release from the NIMH, which funded the study.

"These results underscore the importance of early diagnosis and treatment with antiretroviral therapy," Rausch said.

Further research is needed to determine if the potential brain damage caused by early HIV infection is reversible with antiviral therapy, said study co-author Ronald Swanstrom, of the University of North Carolina at Chapel Hill.

-- Robert Preidt

Article Credits / Source

Robert Preidt / HealthDay

Robert Preidt wrote this story for HealthDay. HealthDay provides up to the minute breaking health news. Click here to view this full article from HealthDay.

SOURCE: U.S. National Institute of Mental Health, news release, March 26, 2015

View More Articles From Robert Preidt 🌎View Article Website

Sponsored Product

Lunar Sleep for $1.95

Lunar Sleep for $1.95

People who have trouble sleeping typically have low levels of melatonin, so melatonin supplements seem like a logical fix for insomnia. There is a high demand for sleep aids, especially in the U.S. The National Health Interview Survey done in 2002, and again in 2007, found 1.6 million US adults were using complementary and alternative sleep aids for insomnia. Lunar Sleep was a top choice. Use Promo Code: Sleep2014 and only pay $1.95 S&H.

Get Lunar Sleep for $1.95

More HIV Articles

Drug Combo Shows Early Promise for Remission of HIV

Drug Combo Shows Early Promise for Remission of HIV0

THURSDAY, Nov. 10, 2016 (HealthDay News) -- Animal research with an experimental two-drug therapy could hold clues for creating long-term HIV remission in people living with the virus, a new report says. The goal: to free patients from the need ...

Antibodies May Hold Key to HIV Suppression

Antibodies May Hold Key to HIV Suppression0

WEDNESDAY, Nov. 9, 2016 (HealthDay News) -- Antibodies may keep the HIV virus in check and one day let patients stop taking antiretroviral drugs, two new preliminary trials suggest. Researchers tried to quell HIV in 23 patients with infusions ...

Experimental Medicine Might Rescue People With Drug-Resistant HIV

Experimental Medicine Might Rescue People With Drug-Resistant HIV0

FRIDAY, Oct. 28, 2016 (HealthDay News) -- Researchers report that a new medication might revolutionize the treatment of HIV patients who don't respond to existing drugs. The intravenous drug, known as ibalizumab, is given every two weeks. It's ...

Study Discounts Myth of 'Patient Zero' in U.S. AIDS Crisis

Study Discounts Myth of 'Patient Zero' in U.S. AIDS Crisis0

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- Using genetic analyses of 40-year-old blood samples, scientists have arrived at a clearer understanding of the introduction and spread in North America of the virus that causes AIDS. One myth already ...

HIV May Hide in Tissues, Even After Treatment

HIV May Hide in Tissues, Even After Treatment0

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- HIV patients who've been treated with antiretroviral drugs still have the AIDS-causing virus in their tissues, a new study suggests. Treatment with antiretrovirals eliminates detectable levels of HIV ...

View More HIV Articles

0 Comments

Write a Comment

Your email address will not be published. Required fields are marked *

Our Mailing List

Subscribe to our mailing list to get the latest health news as it breaks!

Your information will not be shared with anyone!