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Combivir (lamivudine and zidovudine)

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Pharmacy Author: Omudhome Ogbru, PharmD Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

Medical and Pharmacy Editor: Jay W. Marks, MD Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

ARTICLE RELATED DISEASES IMAGES & QUIZZES INDEX HIV AIDS Myths and Facts Slideshow Pictures Take the HIV/AIDS Quiz AIDS Retrospective Slideshow Pictures GENERIC NAME: lamivudine and zidovudine (3tc/ZDV)BRAND NAME: Combivir

GENERIC AVAILABLE: Yes.

PRESCRIPTION: Yes.

USES:

Combivir is used, in combination with other agents, for the treatment of HIV infection.

WARNING: (BLACK BOX WARNING):

Zidovudine may cause low red and white blood cells. Long term use of zidovudine may lead to muscle damage. Lactic acidosis, severe hepatomegaly with steatosis, including fatal cases, may occur from use of lamivudine or zidovudine. Severe acute flare up of hepatitis B has been reported in patients infected with hepatitis B virus and human immunodeficiency virus after stopping lamivudine. Liver function should be monitored in these patients and anti-hepatitis B treatment should be started if needed

Medically Reviewed by a Doctor on 9/20/2016

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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lamivudine and zidovudine on RxList Need help identifying pills and medications?

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Watch this slideshow to get a historical overview of the HIV/AIDS pandemic from human contraction to the present.

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