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brimonidine, (Alphagan, Alphagan P - Discontinued in the US)

👤by AP 0 comments 🕔Monday, April 6th, 2015

DRUG CLASS AND MECHANISM: Brimonidine is is an ophthalmic solution used for the treatment of one type of glaucoma, open-angle glaucoma. In this type of glaucoma, too much fluid (aqueous humor) is made within the eye and causes high pressures within the eye. The pressure damages the nerves in the eye responsible for vision, and this ultimately causes blindness. Brimonidine reduces the body's production of aqueous humor and increases the flow of aqueous humor out of the eye, resulting in a decrease in pressure. It accomplishes this by stimulating alpha type 2 receptors selectively in the eye with less effect on alpha type 2 receptors elsewhere in the body. It is the first drug of its class to be used for glaucoma. Brimonidine was approved by the FDA in 1996.

PRESCRIBED FOR: Brimonidine is used for the reduction of intraocular pressure in patients with open-angle glaucoma.

SIDE EFFECTS: Common side effects include:

dry eyes, red eyes, irritation of the eyes, headache, blurred vision, a sensation of a foreign body in the eye, and drowsiness.

Medically Reviewed by a Doctor on 4/6/2015

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Pharmacy Author:

Omudhome Ogbru, PharmD

Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

Medical and Pharmacy Editor:

Jay W. Marks, MD

Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Article Credits / Source

AP / MedicineNet.com

AP wrote this story for MedicineNet.com. MedicineNet.com provides up to the minute breaking health news. Click here to view this full article from MedicineNet.com.

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