Daily Health Headlines

sibutramine (Meridia)

👤by MedicineNet.com 0 comments 🕔Monday, October 12th, 2015

DRUG CLASS AND MECHANISM: Sibutramine is a medication that assists with weight-loss by altering neurotransmitters within the brain. Neurotransmitters are chemicals that are produced and released by nerves in order to communicate with other nerves. Released neurotransmitters may attach to other nerves or they may be taken up again by the nerves that release them, a process termed reuptake. Sibutramine blocks the reuptake of the neurotransmitters dopamine, norepinephrine, and serotonin. Blocking the reuptake of neurotransmitters alters the balance of neurotransmitters within the nerve cells and thereby affect nerve function and interaction.

Patients taking sibutramine may achieve a 5-10% reduction from their baseline weight. Additionally, sibutramine-assisted weight loss has been accompanied by improvement in blood lipids (e.g, cholesterol). Sibutramine was approved by the FDA in 1997.

PRESCRIBED FOR: Sibutramine is used for weight loss in conjunction with a low calorie diet. Specific populations for whom the medication is recommended are those with an initial body mass index of more than 30 kg/m2 (27 mg/m2 if they also have other risk factors such as diabetes mellitus, high cholesterol or hypertension).

SIDE EFFECTS: In general, sibutramine is well-tolerated. The most common side effects have been:

constipation, inability to sleep, headache, dry mouth, abdominal pain, acne, rash, chest pain, anxiety, joint pain, back pain, excitation, depression, sweating, dizziness, drowsiness, changes in taste, irregular or painful menstrual periods, flu-like syndrome, increased cough, muscle pain, nausea, vomiting, neck pain, nervousness, palpitations, tingling of the extremities, sore throat, and sinus congestion.

Abnormal liver tests have been reported in 1 in 60 persons who receive sibutramine.

Other important side effects include:

depression, psychosis, mania, suicidal thoughts and suicide

However, it has not been established that sibutramine caused these events. If any of these events occur during treatment, sibutramine probably should be discontinued.

Medically Reviewed by a Doctor on 10/12/2015

sibutramine Index sibutramine on RxList

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Need help identifying pills and medications?Use the pill identifier tool on RxList.

Back to Medications Index

Article Credits / Source

MedicineNet.com

MedicineNet.com provides up to the minute breaking health news. Click here to view this full article from MedicineNet.com.

View More Articles From MedicineNet.com 🌎View Article Website

Sponsored Product

Lunar Sleep for $1.95

Lunar Sleep for $1.95

People who have trouble sleeping typically have low levels of melatonin, so melatonin supplements seem like a logical fix for insomnia. There is a high demand for sleep aids, especially in the U.S. The National Health Interview Survey done in 2002, and again in 2007, found 1.6 million US adults were using complementary and alternative sleep aids for insomnia. Lunar Sleep was a top choice. Use Promo Code: Sleep2014 and only pay $1.95 S&H.

Get Lunar Sleep for $1.95

More Diet & Weight Management Articles

Balloon-in-a-Pill Helped Obese Patients Lose Weight

Balloon-in-a-Pill Helped Obese Patients Lose Weight0

FRIDAY, Nov. 4, 2016 (HealthDay News) -- Obese patients who swallowed balloon capsules that helped them eat less lost an average of 15 pounds, roughly two times more weight than patients who just dieted and exercised, researchers report. The ...

Follow-Up Appointments Boost Weight-Loss Surgery Success

Follow-Up Appointments Boost Weight-Loss Surgery Success0

"This study shows there is great value in seeing patients at routine intervals after surgery in terms of health outcomes," said study co-author Dr. Andrea Schwoerer. She was at the Brody School of Medicine at East Carolina University at the time of ...

Skip Dinner and Maybe Boost Your Metabolism

Skip Dinner and Maybe Boost Your Metabolism0

THURSDAY, Nov. 3, 2016 (HealthDay News) -- Overweight people who eat during a much smaller window of time each day than is typical report fewer hunger swings and burn slightly more fat at certain times during the night, according to a new ...

Lack of Sleep May Stretch Your Waistline

Lack of Sleep May Stretch Your Waistline0

THURSDAY, Nov. 3, 2016 (HealthDay News) -- Too little sleep may contribute to a larger waistline, researchers say. The new research included 11 studies with a total of 172 participants. Compared to those who got enough sleep, those who were ...

phentermine (Adipex-P, Lomaira)

phentermine (Adipex-P, Lomaira)0

home / health & living center / diet & weight management a-z list / phentermine index / phentermine (adipex-p, lomaira) drug monograph Pharmacy Author: Omudhome Ogbru, PharmD Omudhome Ogbru, ...

View More Diet & Weight Management Articles

0 Comments

Write a Comment

Your email address will not be published. Required fields are marked *

Our Mailing List

Subscribe to our mailing list to get the latest health news as it breaks!

Your information will not be shared with anyone!