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Repatha (evolocumab)

👤by AP 0 comments 🕔Thursday, September 22nd, 2016
Pharmacy Author: Omudhome Ogbru, PharmD Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

Medical and Pharmacy Editor: Jay W. Marks, MD Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

ARTICLE RELATED DISEASES IMAGES & QUIZZES INDEX A Visual Guide to Heart Disease Medical Illustrations of the Heart Image Collection Take the Heart Disease Quiz! GENERIC NAME: evolocumabBRAND NAME: Repatha




Repatha is used along with diet, exercise and maximum tolerated doses of statins to reduce LDL cholesterol in adults with heterozygous familial hypercholesterolemia (and inherited disorder that causes high levels of LDL) or adults with heart problems related to excess cholesterol in the body. Repatha is also used along with diet and other LDL-lowering treatments, for example, statins, ezetimibe (Zetia) and LDL apheresis, to reduce cholesterol in people with homozygous familial hypercholesterolemia (an inherited disorder that causes high levels of LDL).


The most common side effects associated with Repatha treatment include

injection site reactions, back pain, symptoms of the common cold, and flu-like symptoms.

Other side effects include

diarrhea, muscle pain, muscle spasm, fatigue, urinary tract infections (UTIs), cough, allergic reactions, hypertension, headache, dizziness, joint pain, nausea, confusion, and pancreatitis

A more serious side effect is:

Hypersensitivity reactions: Repatha should not be used in patients with a history of serious hypersensitivity reactions to the product. Hypersensitivity reactions include itching, rash, and hives, have occurred. Repatha should be discontinued if signs or symptoms of serious allergic reactions occur.

Medically Reviewed by a Doctor on 9/22/2016

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