Daily Health Headlines

Many Patients Enter Cancer Trials With Unrealistic Expectations

👤by Mary Elizabeth Dallas 0 comments 🕔Monday, September 26th, 2016

MONDAY, Sept. 26, 2016 (HealthDay News) -- Many cancer patients hold unrealistic hopes when they decide to join early stage clinical trials of experimental treatments, new research shows.

These trials -- known as phase 1 trials -- evaluate the safety and possible benefits of treatments that have never before been tested on people.

Many of these trials are limited to patients who have advanced disease or who have not responded to other treatments.

Usually, patients start a trial on a low dose of medication and gradually get bigger doses until a recommended level is set for a new phase 2 trial.

After talking to their doctor about the possible risks and benefits of phase 1 trials, a high percentage of cancer patients were willing to participate, but nearly half believed their tumor would shrink as a result, the new study found.

British researchers asked 396 cancer patients who were considering enrollment in a phase 1 trial to complete a questionnaire about reasons why they wanted to take part. Without a discussion of potential risks and benefits, 43 percent predicted their tumor would shrink.

After meeting with their doctor, 301 patients completed a second questionnaire. Once they had learned more about the trials, 47 percent predicted their tumor would shrink.

The study authors said this percentage is much higher than realistic for early stage studies. Median survival for patients in phase 1 trials is six months, meaning half live less time, half more.

Patients were eager to enlist in trials. Before talking with their doctor, 72 percent said they would consider enrolling. After a discussion, 84 percent were willing to join, the study found.

It was published online Sept. 26 in the journal Cancer.

"There is a positive message in this, which is that 84 percent of patients are willing to participate in phase 1 oncology studies after a discussion with clinical and nursing staff who lay out the conservative estimates of benefit and requirements of hospital visits," study lead author Dr. Udai Banerji said in a journal news release. Banerji is deputy director of the Drug Development Union at The Institute of Cancer Research in London.

"This is good for current and future patients and cancer medicine in general," he said.

But, Banerji called the high percentage of cancer patients who expected their tumor to shrink a red flag.

"This creates a challenge for health care professionals to manage expectations but to do so without being patronizing or dismissing human hope," he said.

-- Mary Elizabeth Dallas

Article Credits / Source

Mary Elizabeth Dallas / HealthDay

Mary Elizabeth Dallas wrote this story for HealthDay. HealthDay provides up to the minute breaking health news. Click here to view this full article from HealthDay.

SOURCE: Cancer, news release, Sept. 26, 2016

View More Articles From Mary Elizabeth Dallas 🌎View Article Website

Sponsored Product

Lunar Sleep for $1.95

Lunar Sleep for $1.95

People who have trouble sleeping typically have low levels of melatonin, so melatonin supplements seem like a logical fix for insomnia. There is a high demand for sleep aids, especially in the U.S. The National Health Interview Survey done in 2002, and again in 2007, found 1.6 million US adults were using complementary and alternative sleep aids for insomnia. Lunar Sleep was a top choice. Use Promo Code: Sleep2014 and only pay $1.95 S&H.

Get Lunar Sleep for $1.95

More Cancer Articles

No Benefit From Routine Thyroid Cancer Screening: Task Force

No Benefit From Routine Thyroid Cancer Screening: Task Force0

TUESDAY, Nov. 22, 2016 (HealthDay News) -- Doctors should not screen for thyroid cancer in patients who have no symptoms of the disease, according to a U.S. Preventive Services Task Force draft recommendation. It reaffirms a recommendation ...

Depressed Women Less Likely to Get Best Breast Cancer Care: Study

Depressed Women Less Likely to Get Best Breast Cancer Care: Study0

FRIDAY, Nov. 18, 2016 (HealthDay News) -- Breast cancer patients with a history of depression are less likely to receive recommended care for their disease, a new study finds. The study included more than 45,000 Danish women diagnosed with ...

Earnings Fall After a Child's Cancer Diagnosis

Earnings Fall After a Child's Cancer Diagnosis0

MONDAY, Nov. 21, 2016 (HealthDay News) -- After a child's cancer diagnosis, parents' income often drops and mothers frequently stop working, a new study finds. Moreover, the financial effects of a cancer diagnosis can last years, with mothers' ...

Monoclonal Antibodies

Monoclonal Antibodies0

home / cancer center / cancer a-z list / monoclonal antibodies index / monoclonal antibodies drug monograph Pharmacy Author: Omudhome Ogbru, PharmD Omudhome Ogbru, PharmDDr. Ogbru received his ...

New Drug May Brighten Outlook for Advanced Breast Cancer

New Drug May Brighten Outlook for Advanced Breast Cancer0

WEDNESDAY, Nov. 16, 2016 (HealthDay News) -- A recently approved drug can help slow the progression of advanced breast cancer, a new clinical trial confirms. The drug, called palbociclib (Ibrance), was approved in the United States last year ...

View More Cancer Articles

0 Comments

Write a Comment

Your email address will not be published. Required fields are marked *

Our Mailing List

Subscribe to our mailing list to get the latest health news as it breaks!

Your information will not be shared with anyone!