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ciclesonide (Alvesco)

👤by AP 0 comments 🕔Wednesday, November 4th, 2015

DRUG CLASS AND MECHANISM: Ciclesonide (Alvesco) is a man-made steroid for inhalation in the glucocorticoid family. It is related to the naturally-occurring steroid hormone, cortisol or hydrocortisone, produced by the adrenal glands. The body converts ciclesonide to des-ciclesonide, which is the active form of the drug. Glucocorticoid steroids have potent anti-inflammatory actions. When used as an inhaler, ciclesonide travels to the airways in the lung. In people with asthma, the suppression of inflammation within the airways reduces the spasm of muscle cells that surround the airways as well as the accumulation of fluid and cells that accompanies the inflammation which lead to narrowing of the airways. The narrowing makes it difficult to get air into and out of the lungs. When used in lower doses, very little ciclesonide is absorbed into the body. When higher doses are used, ciclesonide is absorbed and may cause side effects elsewhere in the body. The FDA approved ciclesonide in January 2010.

PRESCRIBED FOR: Ciclesonide is used in individuals 12 years of age or older for the treatment of asthma.

SIDE EFFECTS: The most common side effects associated with ciclesonide are:

Headache Sinusitis Common cold Throat pain Upper respiratory infection Joint pain (arthralgia) Nasal congestion Pain in the extremities Back pain

Other side effects or adverse reactions include:

Oral fungal infections (candidiasis) Higher doses of ciclesonide may cause suppression of the body's ability to make its own natural glucocorticoid in the adrenal gland. People with suppression of their adrenal glands (which can be diagnosed by a doctor) would need increased amounts of glucocorticoids, probably by the oral or intravenous route, during periods of high physical stress or acute illness when glucocorticoids are particularly important. Inhaled steroids may cause growth suppression in children, weaken the immune system, and may increase the risk of glaucoma, and cataracts. Allergic reactions may occur, including swelling of face, throat and tongue, as well as rash, hives, and breathing problems.

Medically Reviewed by a Doctor on 11/4/2015

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Pharmacy Author:

Omudhome Ogbru, PharmD

Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

Medical and Pharmacy Editor:

Jay W. Marks, MD

Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Article Credits / Source

AP / MedicineNet.com

AP wrote this story for MedicineNet.com. MedicineNet.com provides up to the minute breaking health news. Click here to view this full article from MedicineNet.com.

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